Patient Medication Information

• Acts on the pituitary gland to desensitise (down-regulate) prior to commencing a stimulation cycle.
• Can also be used to Trigger for the final maturation of oocytes prior to egg collection.
• Treatment may begin in the early follicular phase (Day 2 of cycle) or the mid-luteal phase (usually Day 21 of the preceding cycle) or to trigger final maturation (end of stimulation).
• Causes an initial and transient increase in the pituitary hormones (LH and FSH) – leading to a temporary increase in ovarian hormone production.
• Repeated dosing, leads to a decrease in the secretion of LH and FSH from the pituitary gland – resulting in a reduction in ovarian hormone production. This provides a more controlled situation for stimulating follicle production.
• Down-regulation of the pituitary can prevent the LH surge –thereby preventing premature ovulation.

• Headaches
• Hot flushes
• Mood swings
• Vaginal dryness
• Changed in libido
  

Synarel: store below 25ºC and away from light.
Lucrin: refrigerate (2-8 degrees) Do not freeze.
Decapeptyl: refrigerate (2-8 degrees) Do not freeze.

Gonal F or Puregon or Menopur or Bemfola or Rekovelle and Elonva

Acts directly on the ovaries to stimulate follicular development and hormone production within the ovaries with the aim of collecting multiple mature eggs at egg collection.

• Headaches
• Dizziness
• Pelvic pain
• Pelvic discomfort
•  Nausea
• Fatigue
• Tender breasts
• Mood swings
•  Fluid retention
• Ovarian Hyperstimulation Syndrome (OHSS)
  

Refrigerate (2-8 degrees). Do not freeze.

Luveris

Store below 25 degrees. Protect from light.

Pergoveris

• Cetrotide: store below 30 degrees.
• Orgalutran: store below 30 degrees.

Ovidrel or Pregnyl or GnRH Agonist