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Intracytoplasmic Sperm Injection (ICSI) is a specialised form of In Vitro Fertilisation (IVF) that is used for the treatment of severe cases of male factor infertility. ICSI is usually recommended where there is low sperm count, a high number of abnormally shaped sperm, reduced sperm motility, no sperm in a semen analysis or following an unsuccessful vasectomy reversal. It is also recommended for couples who have had previous cycles where standard IVF has resulted in reduced or no fertilisation.
The process of ICSI involves the injection of a single sperm directly into a mature egg by a skilled embryologist.
This differs from standard IVF, where multiple sperm are added to the eggs in a special dish and left to fertilise without intervention from an embryologist.
The purpose of ICSI is to improve the chances of fertilisation in cases where standard IVF may not be successful. The process involves selection of a single swimming sperm for injection into a single mature egg. Every mature oocyte (egg) retrieved is injected and then assessed for fertilisation 16-18 hours post injection.
To learn more about the ICSI procedure, please read our fact sheet: ICSI or visit our Patient information booklets page. You can also view our ICSI PDF to find out more about the process.
ICSI is recommended for couples who have experienced a cycle with reduced or no fertilisation using standard IVF. It may also be used for couples where the male partner has been diagnosed with:
Please remember anyone can be affected by infertility and while it can be a challenging experience, the good news is that our fertility specialists are here to help you explore all available options to achieve your dream of having a baby.